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Faculty
Mazhar Khan
Background
Education
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Ph.D. (Comparative Pathology) University of California, Davis, California
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M.P.V.M. (Preventive Veterinary Medicine) University of California, Davis, California
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D.V.M. (Veterinary Medicine) University of Punjab, Lahore, Pakistan
Professional Experience
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Professor, Department of Pathobiology, University of Connecticut, Storrs, CT, 2003 to present.
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Associate Professor, Department of Pathobiology, Joint Appointment, University of Connecticut, Storrs, CT, May 1, 1996 to 2003
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Head, Avian Diagnostic Pathology, Connecticut Veterinary Diagnostic Laboratory, Department of Pathobiology, Storrs, CT. July 1, 1993 to present
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Assistant Professor, Department of Pathobiology, University of Connecticut, Storrs, CT, September 1, 1989 to August 31, 1995.
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Molecular Biologist/Virologist, USDA, ARS, Southeast Poultry Research Laboratory, Athens, GA, January 15, 1989 to August 31, 1989.
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Postdoctoral Researcher, Department of Avian Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA, July 1, 1988 to January 14, 1989.
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Postdoctoral Researcher, Department of Epidemiology & Preventive Medicine, School of Veterinary Medicine, University of California, Davis, CA., December 1, 1987 to June 30, 1988.
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Postgraduate Researcher, Department of Epidemiology & Preventive Medicine, School of Veterinary Medicine, University of California, Davis, CA., July1, 1985 to December 31, 1987.
Professional Memberships
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American Association of Avian Pathologists (AAAP). - American Veterinary Medical Association (AVMA) - American Association of Extension Veterinarians (AAEV) - American Association of University Professors (AAUP) - American Society for Microbiology (ASM) - Connecticut Poultry Association (CPA) - World Poultry Science Association (WPSA) - Gamma Sigma Delta
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University, College and Other Professional Committees and activities:
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Member, Faculty Standards Committee, University of Connecticut Senate. 1996-1999.
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Member, Student Welfare Committee, University of Connecticut Senate. 1992-1994.
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Member, Sub-committee on Grades Change, Faculty Standards Committee, 1998-1999.
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Member, Curricular and Courses Committee, College of Agriculture and Natural Resources, University of Connecticut, Storrs. 1989-1999.
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Member, Committee for Equal Opportunity Employment, College of Agriculture and Natural Resources, University of Connecticut, Storrs. 1992-1993.
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Member, Biotechnology Liaison Committee, College of Agriculture and Natural Resources, University of Connecticut, Storrs. 1993-1995.
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Member, Diversity Committee, College of Agriculture and Natural Resources, University of Connecticut, Storrs. 1997-1999.
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Member, International Activities Committee, College of Agriculture & Natural Resources, University of Connecticut, Storrs. 2000-present
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Member, Alumni Awards Committee, College of Agriculture & Natural Resources, University of Connecticut, Storrs. 1999-2000.
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Member, Food-safety Committee, College of Agriculture & Natural Resources, University of Connecticut, Storrs. 1999-present
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Member, Faculty Candidate Search Committee, Department of Pathobiology, 1991.
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Member, Faculty Candidate Search Committee, Department of Pathobiology, 1992.
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Member, Department of Pathobiology's Graduate Student Selection Committee. 1992-1996.
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Member, Department Head Search Committee. Department of Pathobiology, Member. 1994.
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Member, Department of Pathobiology's Promotion, Tenure and Reappointment Committee. 1995-1997.
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Member, Department of Pathobiology's Merit Committee. 1994-1996
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Member, Biotechnology Committee, American Veterinary Medical Association, 1990-present
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Member, Avian Respiratory Diseases Committee, American Veterinary Medical Association, 1995-2000
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Member, USDA Multi-state Research Project, Epidemiology and control of emerging strains of poultry disease respiratory agents. NE 138, 1990-1993.
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Member, Planning Advisory Committee, Member, New England Poultry Management Conf. 1990-present
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Member, Planning Advisory Committee, Member, New England Poultry Health Conference. 1990-2000.
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Member, Planning Advisory Committee, Member, New England Pest Control Meeting, Member, 1990-1993.
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Member, Mycoplasma Committee, Northeastern Poultry Disease Conference. New England Division. Member. 1990- present
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Member, Avian Mycoplasma advisory Committee. International Organization of Mycoplasmologists. 1987-1998
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Member, Salmonella Committee, Member, Northeastern Conference on Avian Diseases. Member, 1992-present
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Member, Department of Pathobiology's Graduate Student Selection Committee. 2000-present
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Member, Student Awards Committee, 66th Annual meeting of Northeastern Conference of Avian Diseases. College Park, Maryland. June, 1994.
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Faculty advisor to Vietnam Student Association, 1992 to 1994.
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Faculty advisor to Asian American Culture Center, 1993.
Leadership Activities
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Chairman, Department of Pathobiology's and Curricular and Courses, 1990-1996.
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Chairman of Session. Mycoplasma Infection. 129th Annual Meeting of American Veterinary Medical Association, Boston, Massachusetts. August, 1992.
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Chairman of Session: Vaccination Program: Annual Meeting of New England Poultry Management Conference, Andover, Massachusetts, .September 1992.
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Chairman of Session. Mycoplasmosis. 42nd Western Poultry Disease Conference, Sacramento, California, March, 1993.
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Chairman of Session. Salmonella enteritidis infection: Annual meeting of 65th Northeastern Conference of Avian Disease. University of Delaware, Newark, Delaware. June, 1993.
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Chairman of Session: Poultry Health Surveillance in New England. 43rd Annual Meeting of New England and New York Poultry Health Conference, Portsmouth, New Hampshire. March 1994.
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Secretary, USDA Multi-state Research Project, Epidemiology and control of emerging strains of poultry disease respiratory agents. NE 138, 1994-1995.
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Program Chairman, 67th Northeastern Conference on Avian Diseases, Mystic, Connecticut. June 12-14, 1995.
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Chairman, Biotechnology Committee, American Veterinary Medical Association. 1995-1997.
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Vice Chairman , USDA Multi-state Research Project, Epidemiology and control of emerging strains of poultry disease respiratory agents. NE 138, 1995-1996.
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Chairman, Department of Pathobiology's Merit Committee. 1996.
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Chairman of Session: Avian Mycoplasma. XIth WVPA International Congress, Budapest, Hungary. August 18-22, 1997.
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Chairman of Session: Communicable disease diagnosis. 7th International Conference of the Egyptian Society for Infection Control. Cairo, Egypt, October 28, 1998.
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Chairman of Session: Avian Influenza update. 43rd Annual Meeting of New England and New York Poultry Health Conference, Portsmouth, New Hampshire. March 1999.
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Secretary, USDA Multi-state Research Project, Epidemiology and control of emerging strains of poultry disease respiratory agents. NE 138, 1999-2000.
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Chairman of Session: Animal Pathology: International Conference on Animal Science and Veterinary Medicine towards the 21st Century. Beijing, P. R. China. August 12-15, 2000.
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Program Chairman, Polymerase Chain Reaction (PCR) Symposium, Biotechnology, American Association Avian Pathologists (AAAP). Salt Lake City, Utah, July, 1999-2000.
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Chairman of Session: PCR for bacteria, Symposium, Biotechnology AAAP, Salt Lake, Utah. July, 2000.
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Program Chairman, University of Connecticut Poultry Health and Management Conference, April 18 2001.
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Program Chairman Elected. 74th Northeastern Conference on Avian Diseases, to be held in Connecticut. June 12-14, 2001.
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Panel Member, National Research Initiative Competitive Grant Program, USDA, Food Safety. April 30-May 2, 2003.
Scholarships and Awards
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Listed in Who's Who in the South East. 1990-1994
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Listed in Who's Who of Emerging Leaders in America. 1993
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Scholarship from the Livestock Disease Research Laboratory, School of Veterinary Medicine, University of California, Davis, CA. Ph.D. Research. 1987-1988
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Scholarships from the Pacific Egg and Poultry Association for graduate study at the University of California, Davis. 1986 and 1987.
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Distinction in Veterinary Parasitology, from the University of Punjab, Lahore. 1968.
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Scholarship from Agriculture Department of Baluchistan to study Veterinary Medicine at the University of Punjab, Lahore. 1965 to 1970.
Ad hoc Reviewer
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USDA National Competitive grants programs
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Bi-national Agriculture Development grant (BARD)
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Research Foundation grants, University of Connecticut
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American Journal of Veterinary Research
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Journal of Veterinary diagnostic Investigation
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Storrs-Experiment Station, University of Connecticut
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Massachusetts Experiment Station, University of Massachusetts, Amherst, MA. Competitive Research Grant Program, University of Delaware, Newark, DE.
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Academic Initiation Grant. North Carolina's Biotechnology Center, Research Park, NC.
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Molecular and Cellular Probes
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Veterinary Research Communications, UK
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Contact
Email: MAZHAR.KHAN@UConn.edu
Phone: 860 486-0228 fax: 860 486-2794
Department of Pathobiology and Veterinary Science
The University of Connecticut
61 North Eagleville Road, Unit-3089
Storrs, CT 06269-3089
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Courses Taught
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PVS 252- Pathobiology of Avian Species. A three credit hours undergraduate course, 1994-current. Solo.
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PVS 295W- Pathobiology Seminar.-current team taught
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SAPB 015- Diseases of Farm Animals and Poultry. A three credit hours, undergraduate course, 1993-current team taught, (30%).
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PVS 339- Avian Pathology. A two credit hours, graduate course, 1994. Solo.
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PVS 357- Evaluation of Diagnostic tests. 2 credit hours, graduate course, 1998-current Evaluation of Diagnostic tests. Solo.
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PVS 445 & Path 446, Veterinary Diagnostic Pathology, Co-Instructor for Pathology residents in avian diagnostic pathology.
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Research Interests
- Molecular Diagnostic Techniques: Development and application of DNA based probes , PCR, Multiplex PCR for avian pathogenic mycoplasmas (Mycoplasma gallisepticum (MG), Mycoplasma synoviae (MS), Mycoplasma meleagridis (MM) and Mycoplasma iowae (MI)), RT-PCR, PCR and Multiplex PCR for Reovirus, Adenovirus and infectious bronchitis virus (IBV), Salmonella spp. Campylobacter spp. (Food-borne pathogens) and meat spoilage bacteria (PCR, Quantitative and Multiplex PCR).
- Molecular Epidemiology: Arbitrarily primed (AP) PCR fingerprinting for Salmonella enteritidis isolates of avian and human origin. Ribotyping and AP-PCR for Proteus spp, ERIC-PCR for serovar differentiation of Hemophilus paragallinarum.
- Pathogenesis of Salmonella enteritidis (SE) and mechanism of attachment, adhesion molecules and host receptors. Vaccine and SE specific diagnostic tests development.
- Molecular characterization of S genes of infectious bronchitis virus (IBV). Pathogenesis of IBV serotypes. Development of recombinant DNA-vectored vaccine for infectious bronchitis virus (IBV). In ovo vaccination trial of recombinant DNA vaccine for IBV.
- Molecular diagnosis (PCR) of Lyme disease in animals
- Pathogenesis and Surveillance of Avian Influenza virus outbreaks in New England.
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Publications
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Khan, M. I., B. C. Kirkpatrick, and R. Yamamoto. Species and strain specific recombinant DNA probes of Mycoplasma gallisepticum. Avian Pathol. 18:135-146, 1989.
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Khan, M. I., and R. Yamamoto. Differentiation of the vaccine F-strain from other strains of Mycoplasma gallisepticum by restriction endonuclease analysis. Vet. Microbiol. 19: 167-174, 1989.
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Kleven, S. H., M. I. Khan, and R. Yamamoto. Fingerprinting of Mycoplasma gallisepticum strain isolated from multi-age layer with live F strain. Avian Dis. 34: 984-990, 1990.
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Nascimento, E. R., R. Yamamoto, and M. I. Khan. Mycoplasma gallisepticum vaccine strain-polymerase chain reaction. Avian Dis. 37:203-211, 1993.
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Khan, M. I., and S. H. Kleven. Detection of Mycoplasma gallisepticum in field samples using a species-specific DNA probe. Avian Dis. 37:880-883, 1993.
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Khan, M. I. Mycoplasma profiling. Symposium on Newly Emerging and Re-Emerging Avian Diseases: American Association Avian Pathologist. Minneapolis, MN, July 18, 1993. p 6-8, 1993.
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Nguyen, A. V., M. I. Khan, and Z. Lu. Amplification of Salmonella chromosomal DNA using polymerase chain reaction. Avian Dis. 38: 119-126, 1994.
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Khan, M. I., and A. V. Nguyen. A salmonella-specific DNA probe and its use in Southern hybridization for differentiation of Salmonella enteritidis. Avian Dis. 39: 368-374, 1995.
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Fadl, A. A., M. I. Khan, and A. V Nguyen. Analysis of Salmonella enteritidis isolates by Arbitrarily Primed PCR. J Clinical Micobiol. 33: 987-989, 1995.
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Blackall, P. J., M. I. Khan, X. Chen, C. Song, and R. Bowles. Development of tests for serovar-specific identification and typing of Haemophilus paragallinarum" DAQ 226A: Final Report: DPI, Queensland. p1-22. 1997.
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Venkitanarayanan, K., C. Faustman, J. F. Crivello, M. I. Khan, T. A. Hoagland and B. W. Berry. Rapid estimation of spoilage bacterial load in aerobicall stored meat by a quantitative polymerase chain reactin. J. Appl. Microbiol. 82: 359-364, 1997.
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Fadl, A. A., and M. I. Khan. Genotypic evaluation of Salmonella enteritidis isolates of known phage types by arbitrarily primed PCR. Avian Dis. 41:732-737, 1997.
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Molinari Clark, K. A., M. I. Khan, H. J. Van Kruiningen and S. L. Bushmich. Experimental infection of neonatal calves with Borrelia burgdorferi. J. Spirochete and Tick-Borne Dis. 4: 49-57, 1998.
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Wang, X., and M. I. Khan. A multiplex PCR for Massachusetts and Arkansas serotypes of infectious bronchitis virus. Molecular and Cellular Probes. 13: 1-7, 1999.
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Xie, Z., M. I. Khan, A. A. Fadl, and T. Girshick. Detection of Avia Adenovirus by polymerase chain reaction. Avian Dis.43: 98-105, 1999.
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Mansy, M. S., M. S. E. Ashour, and M. I. Khan. Development of Species specific polymerase chain reaction (PCR) technique for Proteus mirabilis. Molecular and Cellular Probes. 13: 133-140, 1999.
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Wang, X., and M. I. Khan. Use of RT-PCR-RFLP to examine the interaction between infectious bronchitis virus strains Massachusetts 41 and JMK in ovo. Avian Pathol. 29. 441-448, 2000.
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Blackall, P. J., M. I. Khan. PCR and ERIC-PCR tests for the detection and differentiation of Haemophilus pargallinarum. Symposium on Molecular Identification and Epidemiology of Avian Pathogens. 2, 11-15. 2000.
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Wang, X., and M. I. Khan. Molecular Characterization of an Infectious Bronchitis virus strain isolated from an outbreak in vaccinated layers. Avian Dis. 44. 1000-1006, 2000.
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Trirunavukkarasu Annamalai, Kumar S. Venkitanarayanan, Thomas A. Hoagland, and M. I. Khan. Inactivation of Escherichia coli O157:H7 and Listeria monocytogenes by PR-26 , a synthetic antibacterial peptide. J of Food Protection. 64, 1929-1934. 2001.
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Maria-Soledad P., M. I. Khan and R. A. French. Development of a multiplex PCR for the detection of Haplosporidium nelsoni, Haplospridium costale and Perkinsus marinus in the eastern oyster (Crassostree virginica, Gmelin, 1971). Molecular and Cellular Probes. 15:385-390. 2001.
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Fadl, A. A., K. S. Venkitanarayanan and M. I. Khan. Expression and Characterization of Salmonella enteritidis out membrane proteins expressed during attachment to human epithelial cells. J.Applied Microb. 92:180-186, 2002.
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Pang, Yao-shan., M. I. Khan, H. Wang, Z. Xie and T. Girshick. Multiplex PCR and its application in experimentally infected SPF chickens with respiratory pathogens. Avian Dis. 46:691-699. 2002.
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Wang, X., W.M. Schnitzlein, D. N. Tripathy T. Theodore and M. I. Khan. Construction and immunogenicity studies of recombinant fowlpox virus containing the S1 gene of Massachusetts 41 strain of infectious bronchitis virus. Avian Dis. 46:831-838. 2002.
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Khan, M. I. Multiplex PCR of Avian Pathogenic Mycoplasmas. PCR detection of Microbial Pathogens. In: Methods in Molecular Biology. eds. J. Frey and K. Sachse. Humana Press Inc. Totowa, NJ. pp 223-229, 2003.
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Khan, M. I., A. A, Fadl, and V. K. Venkitanarayanan. 2003 Reducing colonization of Salmonella enteritidis in chicken by targeting outer membrane proteins. J. Applied Microb. 95:142-145.
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Caterina, K. M., S. Frasca Jr, T. Girshick and M. I. Khan. Development of a multiplex PCR for detection of avian adenovirus, avian reovirus, infectious bursal disease virus and chicken anemia virus. Molecular and Cellular Probes. 18:293-298. 2004.
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Fabis, J. J and M. I. Khan. In vivo expression of IBV-S gene in chicks inoculated with recombinant DNA vaccine in ovo. IV. Symposium on Avian Corona & Pneumovirus infections, Rauischholzhausen, Germany, 20-23 June 2004. p.232-236. 2004.
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Vasudevan, P., P. Marek, M. K. M. Mohan, T. Annamalai, M. Darre. M. I. Khan and K. Venkitanarayanan. In vitro inactivation of Salmonella Enteritidis in chicken cecal counts by caprylic acid. Journal of Applied Poultry Reserch. 14:122-125. 2005.
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Zhiqin Xie, , Mazhar I. Khan, Theodore Girshick and Zhixun Xie. Reverse Transcriptase Polymerase Chain Reaction to Detect Avian Encephalomyelitis virus. Avian Diseases 49: 227-230. 2005.
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Xie, Zhixun; Yao-shan Pang, Jiabo Liu, Xianwen Deng, Xiaofei Tang, Jianhua Sun and Mazhar I. Khan. A Multiplex RT-PCR for detection of Type A Influenza Virus, and simultaneously differentiate Avian H5, H7, and H9 hemagglutinin Subtypes. Molecular and Cellular Probes. 20:245-249, 2006.
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