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Faculty

Guillermo Risatti

Background

Education

1987 DVM Universidad Nacional de Río Cuarto, Argentina.
1995 MS University of Nebraska-Lincoln; Lincoln, NE., USA.
2000 Ph.D. University of Nebraska Medical Center, Omaha, NE., USA.

Professional Employment Experience

2004-Present. Assistant Professor. Department of Pathobiology, University of Connecticut, Storrs, CT.
2001-2004. Microbiologist. Exotic Viral Diseases Research, Plum Island Animal Disease Center, Greenport, NY.
2000-2001. Research Associate. Department of Veterinary and Biomedical Sciences, University of Nebraska- Lincoln and Plum Island Animal Disease Center, Agricultural Research Service, USDA, Greenport, NY.
1987-1992. Instructor. Area: Infectious Diseases of Domestic Animals. Department of Animal Pathology, School of Veterinary Medicine, Universidad Naçional de Río Cuarto, Argentina.

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Contact

Dr. Guillermo Risatti
Department of Pathobiology and Veterinary Science
University of Connecticut
61 North Eagleville Road

Storrs, CT 06269-3089
Phone: 860-486-6150
FAX: 860-486-2794

Email: Guillermo.Risatti@UConn.edu

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Courses Taught

  • PVS 378. Molecular Approaches to Disease Diagnosis and Prevention.

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Research Interests

Classical swine fever virus

Porcine reproductive and respiratory syndrome virus (PRRSV)

"Classical Swine Fever Virus: role of the 3'UTR in infectivity of swine." Plum Island Animal Disease Center, ARS, US Department of Agriculture. Specific Cooperative Agreement No 58-1940-5-573. May 2007.

"Role of glycosylation of Classical Swine Fever Virus envelope proteins on virus virulence, antigenicity, and immunogenicity" National Research Initiative (#CONS-2006-01614), US Department of Agriculture. August 2006-August 2009.

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Publications

  • Diagnostic evaluation of a real-time reverse transcriptase PCR assay for the detection of Classical Swine Fever Virus. Risatti, G., Holinka, L., Lu, Z., Kutish, G., Callahan, J., Nelson, W., Brea Tió, E., and M. Borca. 2005. Journal of Clinical Microbiology 43(1): 468-471.
  • Preclinical diagnosis of African Swine Fever in contact exposed swine by a real-time PCR assay. Zsak, L. Risatti, G., French, R., Lu, Z., Kutish, G., Neilan, J., Callahan, J., Nelson, W., and D. Rock. 2005. Journal of Clinical Microbiology 43(1): 112-119.
  • The E2 glycoprotein of classical swine fever virus is a virulence determinant in swine. G. R. Risatti, M. V. Borca, G. F. Kutish, Z. Lu, L. G. Holinka, R. A. French, E. R. Tulman, and D. L. Rock. 2005. Journal of Virology 79(6): 3787-3796.
  • Mutation of E1 glycoprotein of classical swine fever virus affects viral virulence in swine. G.R. Risatti, L.G. Holinka; Z. Lu, G.F. Kutish, E.R. Tulman, R.A. French, J-H. Sur, D.L. Rock, and M.V. Borca. 2005. Virology 343: 116-127
  • Identification of a novel virulence determinant within the E2 structural glycoprotein of classical swine fever virus. G.R. Risatti, L.G. Holinka; C. Carrillo, G.F. Kutish, Z. Lu, E.R. Tulman, I. Fernandez Sainz, and M.V. Borca. 2006. Virology 10; 355(1):94-101.
  • N-linked glycosylation status of Classical Swine Fever Virus strain Brescia E2 glycoprotein influences virulence in swine. GR Risatti, Holinka LG, Sainz IF, Carrillo C, Lu Z, and Borca MV. 2007. Journal of Virology 81(2):924-33.
  • Mutations in the carboxyl terminal region of E2 glycoprotein of classical swine fever virus are responsible for viral attenuation in swine. G. R. Risatti, L. G. Holinka, I. Fernandez Sainz, C. Carrillo, G. F. Kutish, Z. Lu, J. Zhu, D. L. Rock, and M. V. Borca. 2007. Virology 364(2):371-82.
  • Sheeppox virus kelch-like gene SPPV-019 affects virus virulence. C. A. Balinsky, G. Delhon, C. L. Afonso, G. R. Risatti, M.V. Borca R. A. French, E. R. Tulman, S. J. Geary1, and D. L. Rock. 2007 Journal of Virology, 81(20):11392-11401.
  • Classical swine fever virus inhibits nitric oxide production in infected macrophages. Zaffuto K., Borca M., Risatti G.R., Burrage T., Rock D.L., Afonso C., Piccone M.E. 2007. Journal of General Virology, 88 (11): 3007-3012.
  • Removal of a N-linked glycosylation site of classical swine fever virus strain Brescia Erns glycoprotein affects virulence in swine. I. Fernandez Sainz, L. G. Holinka, Z. Lu, G. R. Risatti, and M. V. Borca. 2007. Virology, doi:10.1016/j.virol.2007.08.028. [Epub ahead of print].
  • Fatal Necrotizing Fasciitis and Myositis in a Cat Associated with Streptococcus canis. R. Sura, L. S. Hinckley, G. R. Risatti, and J. A. Smyth. 2007. The Veterinary Record (In press).

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Links

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